Upper and lower respiratory tract infections, Urinary tract infections, Gonococcal urethritis, Acute otitis media, Skin & soft tissue infection.
RofiximÂ® Capsule:Â 1 or 2 capsules (200 mg -400 mg) as a single dose or in 2 divided doses daily for 7-14 days, according to the severity of infection.
RofiximÂ® Powder for Suspension:Â Child dose:Â 8 mg/kg daily as a single dose or in two divided doses for 7-14 days according to the severity of infection or for age; 1/2-1 years:Â 3.75 ml or 75 mg; 1-4 years:Â 5 ml or 100 mg; 5-10 years:Â 10 ml or 200 mg; 11-12 years:Â 15 ml or 300 mg; above 12 years:Â adult dose.
Patients with known hypersensitivity to cephalosporin group of drugs.
Cefixime is generally well tolerated. The majority of adverse reactions in clinical trials were mild and self-limiting in nature. Gastro-intestinal disturbances: diarrhea (if severe diarrhea occurs, RofiximÂ® should be discontinued), changes in the colour of stool, nausea, abdominal pain, dyspepsia, vomiting, flatulence have been reported; Central nervous system disturbances: headache, dizziness; Others: hypersensitivity reactions which usually subsided upon discontinuation of therapy; in frequents and reversible haemotological changes; elevation of serum amylase.
RofiximÂ® should be prescribed with caution in individuals with a history of gastrointestinal diseases, particularly colitis. Dosage adjustment is only necessary in severe renal failure (creatinine clearance <20 ml. min-1).
Store in a cool & dry place, away from direct light.